红球姜 / 野姜 — Zingiber zerumbet (L.) Sm.

Pinyin: Hóngqiújiāng · Malay: Lempoyang / Lempoyang Wangi · Family: Zingiberaceae (姜科)

Energetics

Warm (温)

Flavor

Pungent, slightly bitter, aromatic (辛、微苦、芳香)

Meridians

Spleen (脾), Stomach (胃), Liver (肝)

Traditional Edict

Warms middle burner, transforms dampness, regulates Qi, and expels wind. Traditional Jamu cornerstone for post-natal blood stasis, loss of appetite, and digestive colic.

Cautions & Contraindications

Contraindicated in Yin Deficiency with Fire and active bleeding ulcers. Caution in first trimester of pregnancy.

Clinical Applications

Peptic ulceration, inflammatory bowel disease, osteoarthritic joint pain, non-alcoholic steatohepatitis (NASH), and adjuvant anti-tumorigenic cellular protection.

Quality Markers

Zerumbone (红球姜酮) >= 1.00% (HPLC MHM standard)

Mechanism & Phytochemistry

1. Zerumbone directly inhibits IKK/NF-kB p65 activation, suppressing TNF-a, IL-1b, COX-2, and iNOS. 2. Upregulates gastric mucosal PGE2 and SOD, protecting mucosal integrity. 3. Induces apoptosis in colorectal and hepatic cancer cell lines via Bax/Bcl-2 modulation.

Preparation & Dosage

Sliced dried rhizome decocted 15-20 minutes: 6-15 g daily. Standardized extract: 250-500 mg. Topical warming oil for abdominal binding.

Appended Prescriptions

1. Nanyang Postpartum Uterine Recovery Formula with Curcuma xanthorrhiza and Piper sarmentosum. 2. Gastro-Relief Anti-Ulcer Formulation with Pogostemon cablin and Amomum villosum.

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Yemama Apothecary · Petaling Jaya, Malaysia · For educational and clinical reference only