← Reference library
    Yemama Apothecary

    Bencao Gangmu Reference Library

    Dysentery-Amoebicidal, Anti-Malarial & Bitter Digestive Sovereign (清热燥湿 / 泻火解毒截疟抗阿米巴痢疾健胃消食杀虫 — 传统阿米巴痢疾与恶性疟疾克星木)

    苦林木 / 苦阿魏 / 苦木科白木 / 苦皮树 / 苦榄木 — Simarouba amara Aubl. (syn. Quassia simarouba)

    Pinyin: Kǔlínmù / Kǔ'āwèi · Malay: Kayu Pahit Putih / Pokok Pahit Putih / Marupa · Family: Simaroubaceae (苦木科)

    Botanical Illustration

    Energetics

    Cold (寒 / 苦寒)

    Flavor

    Overwhelmingly bitter, lingering clean bitterness (大苦、极苦、大寒)

    Meridians

    Spleen (脾), Stomach (胃), Large Intestine (大肠), Liver (肝)

    Traditional Edict

    Paradise Tree / White Bitterwood (Kayu Pahit Putih / Ku Lin Mu / Marupa). Intensely bitter white bark and wood. Sovereign natural amoebicide: destroys Entamoeba histolytica in chronic amoebic dysentery, terminates resistant malaria, ignites digestive fire.

    Cautions & Contraindications

    • Extreme clean bitterness (always advise patients). Overdose (>15 g) causes projectile vomiting. CONTRAINDICATED in active bleeding gastric ulcers. CONTRAINDICATED IN PREGNANCY.

    Clinical Applications

    • Intestinal and hepatic amoebiasis (Entamoeba histolytica eradication), chloroquine-resistant malaria (Plasmodium falciparum), severe hypochlorhydric anorexia, and chronic watery diarrhea.

    Quality Markers

    Ailanthin, Glaucarubinone, Glaucarubine & Total Seco-Triterpenoid Quassinoids >= 1.20% (HPLC standard)

    Mechanism & Phytochemistry

    1. Glaucarubinone and ailanthin quassinoids inhibit protein translation and lyse trophozoites in Entamoeba histolytica (IC50 < 0.05 ug/mL). 2. Antiplasmodial schizontocidal action. 3. T2R bitter receptor stimulation of gastric juices.

    Preparation & Dosage

    THE SOVEREIGN MARUPA AMOEBIC DYSENTERY & ANTIMALARIAL DECOCTION: 5 to 10 g dried white bark chips boiled in 500 mL water for 20 min; taken warm in 2 divided doses for amoebiasis or fevers. Stomachic aperitif: 1-2 g wood shavings in hot water.

    Appended Prescriptions

    • 1. The Sovereign Amoebic Dysentery Eradication Synergy with Brucea javanica (Ya Dan Zi) and Coptis chinensis. 2. Rainforest Anti-Malarial Draught with Eurycoma longifolia (Tongkat Ali).

    Enter your email to unlock the full clinical data and formulation notes.

    No spam. Unsubscribe anytime.

    Yemama Apothecary · Petaling Jaya, Malaysia · For educational and clinical reference only