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    Yemama Apothecary

    Bencao Gangmu Reference Library

    Tri-Action Metabolic, Lung-Clearing & a-Glucosidase Antidiabetic Monarch (疏风清热 / 清肺润燥清肝明目降血糖利水消肿降血压滋阴补血 — 浑身是药之植物药王 / 天然降糖DNJ之王)

    桑 / 桑叶 / 桑白皮 / 桑椹 / 桑枝 — Morus alba L. (syn. Morus multicaulis, Morus indica)

    Pinyin: Sāng / Sāngyè / Sāngbáipí / Sāngshèn · Malay: Pokok Mulberi / Mulberi / Bebesaran · Family: Moraceae (桑科)

    Botanical Illustration

    Energetics

    Leaf: Cool (微寒); Bark: Cold (寒); Fruit: Cool (甘寒微凉)

    Flavor

    Leaf: Bitter, sweet (苦、甘); Bark: Sweet, acrid (甘、辛); Fruit: Sweet, sour (甘、酸)

    Meridians

    Leaf: Lung (肺), Liver (肝); Bark: Lung (肺), Bladder (膀胱); Fruit: Heart (心), Liver (肝), Kidney (肾)

    Traditional Edict

    White Mulberry (Pokok Mulberi / Sang). Entire Tree is Medicine. Autumn frost leaves (Shuang Sang Ye) command world's premier a-glucosidase inhibitor (DNJ) for diabetes; root bark (Sang Bai Pi) drains lung-edema and lowers blood pressure; fruit enriches Blood-Yin.

    Cautions & Contraindications

    • Harvest leaves in late autumn after frost (Shuang Sang Ye) for peak active DNJ content. High clinical and culinary safety. Contraindicated in cold watery diarrhea without heat signs.

    Clinical Applications

    • Type 2 Diabetes mellitus (postprandial glucose blunting via competitive intestinal a-glucosidase inhibition), acute bronchitis with dry cough, essential hypertension, and diabetic retinopathy.

    Quality Markers

    1-Deoxynojirimycin (DNJ) >= 1.00%-2.00% in leaves & Mulberroside A >= 1.50% in root bark (Chinese Pharmacopoeia standard)

    Mechanism & Phytochemistry

    1. 1-Deoxynojirimycin (DNJ) competitively inhibits intestinal a-glucosidases (maltase, sucrase), preventing disaccharide breakdown into glucose. 2. Mulberroside A downregulates renal RAAS and vascular eNOS. 3. Anthocyanins retinal protection.

    Preparation & Dosage

    THE SOVEREIGN SHUANG SANG YE GLYCEMIC CLEARING TEA: 10 to 15 g frost-harvested Mulberry leaves steeped in hot water, consumed with meals for diabetes. Sang Bai Pi decoction: 10-15 g daily for hypertension/edema. Fresh berries: 50-100 g.

    Appended Prescriptions

    • 1. Classical Mulberry & Chrysanthemum Cough Decoction (Sang Ju Yin / 桑菊饮) with Platycodon. 2. Glycemic-Lowering Synergy with Momordica charantia (Peria Katak) and Cornsilk.

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    Yemama Apothecary · Petaling Jaya, Malaysia · For educational and clinical reference only