东革阿里 — Eurycoma longifolia Jack

Pinyin: Dōnggé'ālǐ · Malay: Tongkat Ali / Pasak Bumi · Family: Simaroubaceae (苦木科)

Energetics

Warm (温)

Flavor

Extremely Bitter (甚苦)

Meridians

Kidney (肾), Liver (肝), Spleen (脾)

Traditional Edict

Tonifies Kidney Yang, strengthens sinews and bones, dispels fatigue, and cures tropical fevers/malaria. The revered "King of Malaysian Herbs" for male vitality and endurance.

Cautions & Contraindications

Excessive dosages (>1000 mg extract) may cause restlessness or insomnia. Contraindicated in hormone-sensitive prostate cancers, severe cardiac arrhythmias, and pregnancy.

Clinical Applications

Late-onset hypogonadism, idiopathic male infertility, athletic endurance enhancement, adrenal fatigue, osteopenia, and insulin resistance.

Quality Markers

Eurycomanone (东革阿里酮) >= 0.80% (HPLC MHM standard)

Mechanism & Phytochemistry

1. Eurycomanone stimulates CYP17 steroidogenic enzyme, elevating free testosterone biosynthesis and inhibiting aromatase/SHBG binding. 2. Quassinoids activate AMPK pathway, improving glucose uptake. 3. Squalene-type triterpenes exert broad-spectrum antimalarial and anti-inflammatory properties.

Preparation & Dosage

Sliced dried root decocted 30-45 minutes: 2-5 g daily. Standardized extract (100:1 / 200:1): 200-400 mg daily.

Appended Prescriptions

1. Imperial Nanyang Yang-Fortifying Tonic with Morinda officinalis (Ba Ji Tian) and Cistanche. 2. Adaptogenic Vitality Tea with Panax ginseng and Epimedium.

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Yemama Apothecary · Petaling Jaya, Malaysia · For educational and clinical reference only