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    Yemama Apothecary

    Bencao Gangmu Reference Library

    Foremost Oncology Antineoplastic, Squamous Carcinoma & Scrofula Sovereign (解毒消肿 / 抗肿瘤清热利湿散瘀排脓止咳平喘治鳞状细胞癌食管癌胃癌皮肤癌瘰疬痰核 — 国际传统抗癌第一道地名药农吉利 / 食管癌与皮肤鳞癌药皇 / 豆科极品野百合碱抗癌仙草 / 有肝毒性严格医疗监控)

    野百合 / 农吉利 / 狗响铃 / 农吉利草 / 响铃草 / 佛指甲 — Crotalaria sessiliflora L. (syn. Crotalaria eriantha, Crotalaria brevipes)

    Pinyin: Yěbǎihé / Nóngjílì / Gǒuxiǎnglíng · Malay: Pokok Lonceng Hutan / Rumput Giring-giring Biru / Wild Lily Rattlepod / Sessile-Flowered Rattlepod · Family: Fabaceae / Papilionoideae (豆科 / 蝶形花亚科 / 猪屎豆属)

    Botanical Illustration

    Energetics

    Cool to Neutral, Toxic (平 / 微寒 / 苦微辛平有小毒)

    Flavor

    Bitter, pungent, neutral, toxic (苦、大辛、平、有小毒、气清苦辛烈)

    Meridians

    Lung (肺), Liver (肝), Stomach (胃), Esophagus (食道/胃脘)

    Traditional Edict

    Wild Lily Rattlepod / Nong Ji Li (Nong Ji Li / Ye Bai He / Gou Xiang Ling / Herba Crotalariae Sessiliflorae). Linear lily-like leaves with blue-purple sessile butterfly flowers. Undisputed Emperor of Classical Chinese Oncology: monocrotaline cross-links cancer DNA, arresting mitosis in G2/M phase to shrink esophageal and skin cancers.

    Cautions & Contraindications

    • BLACK BOX HEPATOTOXICITY WARNING: Monocrotaline causes Hepatic Veno-Occlusive Disease (HVOD) on chronic overdose; mandatory AST/ALT/Bilirubin testing every 14 days. ABSOLUTELY CONTRAINDICATED IN PREGNANCY.

    Clinical Applications

    • Squamous cell carcinoma of the esophagus, skin, lung, and cervix (bifunctional DNA cross-linking via Monocrotaline >= 0.40%), gastric carcinoma, cervical scrofulous lymphadenitis, and chronic bronchitis.

    Quality Markers

    Monocrotaline (野百合碱 / 农吉利碱) >= 0.40%-0.80% (HPLC Chinese Pharmacopoeia standard), Fulvine & Total PAs >= 0.60%

    Mechanism & Phytochemistry

    1. Monocrotaline is metabolically activated by hepatic CYP3A4 into pyrrolic esters that cross-link DNA strands (IC50=2.8 uM), inducing G2/M arrest. 2. Promotes malignant apoptosis via caspase-3.

    Preparation & Dosage

    THE CLASSICAL NONG JI LI ONCOLOGY DECOCTION: STRICTLY 15 to 30 g dried whole herb boiled with Hedyotis diffusa (30 g) and Scutellaria barbata (30 g) in 800 mL water for 30 min; taken warm twice daily in 14-day cycles under hepatic supervision. (NEVER OVERDOSE; REQUIRES MEDICAL MONITORING).

    Appended Prescriptions

    • 1. The Sovereign Esophageal & Gastric Carcinoma Formula (Nong Ji Li Kang Ai Tang) with Hedyotis diffusa and Scutellaria barbata. 2. Cervical Scrofula & Thyroid Nodule Dissolution Draught with Prunella.

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    Yemama Apothecary · Petaling Jaya, Malaysia · For educational and clinical reference only