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    Yemama Apothecary

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    Central Neuro-Stimulatory, Cognitive Awakening & Hepatic Antifibrotic Sovereign (醒脑开窍 / 提神健脑利水消肿消食降脂祛风止头痛兴奋中枢治神经衰弱嗜睡脑雾偏头痛 — 国际第一高海拔名豆 Kopi Arabika / 脑力提神与偏头痛药皇 / 茜草科极品咖啡因与绿原酸药豆)

    咖啡 / 小果咖啡 / 阿拉比卡咖啡 / 咖啡豆 / 幼果咖啡 — Coffea arabica L.

    Pinyin: Kāfēi / Xiǎoguǒ Kāfēi / Ālābǐkǎ Kāfēi · Malay: Kopi Arabika / Pokok Kopi / Biji Kopi Arabika / Kopi Gunung / Arabian Coffee / Mountain Coffee · Family: Rubiaceae (茜草科 / 咖啡属)

    Botanical Illustration

    Energetics

    Warm (微温 / 苦甘微温芳香)

    Flavor

    Bitter, sweetish, intensely roasted, floral-acidic (苦、甘、微酸、微温、气极芳香清郁)

    Meridians

    Heart (心), Spleen (脾), Stomach (胃), Liver (肝), Bladder (膀胱)

    Traditional Edict

    Arabian Coffee / Highland Coffee (Kopi Arabika / Xiao Guo Ka Fei / Semen Coffeae Arabicae). High-altitude mountain bush with fragrant white flowers and red cherries. Sovereign for Mental Arousal & Vascular Migraines: competitive antagonism at adenosine A1/A2A receptors sharpens alertness, constricts dilated cerebral vessels.

    Cautions & Contraindications

    • Overdose (>500 mg caffeine) may cause palpitations, tremors, insomnia, and reflux. Limit intake in pregnancy to <200 mg daily. Separate from oral iron supplements by 2 hours.

    Clinical Applications

    • Cerebral fatigue, daytime somnolence, and impaired executive focus (adenosine receptor blockade via Caffeine >= 1.20%), vascular migraine attacks (cerebral arteriolar vasoconstriction), and hepatic steatosis with fibrosis.

    Quality Markers

    Caffeine (咖啡因) >= 1.20%-1.80%, 5-CQA Chlorogenic Acid >= 5.0%-8.0% & Trigonelline >= 0.80% (HPLC standard)

    Mechanism & Phytochemistry

    1. Caffeine competitively blocks central adenosine A1/A2A receptors (IC50=1.2 uM), surging dopamine and norepinephrine release. 2. 5-CQA chlorogenic acids inhibit hepatic glucose-6-phosphatase.

    Preparation & Dosage

    FRESHLY BREWED HIGHLAND ARABICA COFFEE: 8 to 12 g freshly ground beans brewed in 150 to 200 mL hot water (92°C) via pour-over or espresso; 1 to 2 cups daily. Standardized green coffee bean extract (50% chlorogenic acids): 200 to 400 mg twice daily before meals. Total caffeine limit: <400 mg daily.

    Appended Prescriptions

    • 1. The Sovereign Highland Brain-Awakening & Focus Brew (Kopi Arabika Minda Cerdas) with raw cacao and cinnamon. 2. Migraine Vascular Constriction Draught with Zingiber officinale.

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    Yemama Apothecary · Petaling Jaya, Malaysia · For educational and clinical reference only