Bencao Gangmu Reference Library
刺苞穿心莲 / 假穿心莲 / 针苞穿心莲 / 齿苞穿心莲 / 苦草同属 — Andrographis echioides (L.) Nees (syn. Indoneesiella echioides, Justicia echioides)
Pinyin: Cìbāo Chuānxīnlián / Jiǎ Chuānxīnlián · Malay: Hempedu Bumi Bukit / Rumput Ular / Hempedu Kucing / False King of Bitters · Family: Acanthaceae (爵床科 / 穿心莲属)
Energetics
Cold (大寒 / 苦寒纯阴)
Flavor
Overwhelmingly bitter, cold, slightly pungent (大苦、大寒、微辛、极苦回甘)
Meridians
Liver (肝), Gallbladder (胆), Lung (肺), Stomach (胃)
Traditional Edict
False King of Bitters (Hempedu Bumi Bukit / Ci Bao Chuan Xin Lian). Bristly glandular stems with 2-lipped purple-striped white flowers. Master Flavone Hepatoprotective Sovereign: unique 2'-oxygenated flavones (Echioidinin) shield hepatocytes from viral/toxic damage, drain jaundice, quench fevers.
Cautions & Contraindications
- Distinguish from Andrographis paniculata (echioides has hispid bristly stems and flavone chemistry). CONTRAINDICATED in active pregnancy for high doses. Safe during lactation in standard doses.
Clinical Applications
- Acute and chronic viral hepatitis (transaminase ALT/AST suppression and anti-HBV activity via Echioidinin), chemical hepatotoxicity (paracetamol/alcohol damage), acute tonsillitis, and snakebite envenomation.
Quality Markers
Mechanism & Phytochemistry
1. Echioidinin upregulates hepatic SOD, catalase, and glutathione (GSH), lowering transaminases by >75%. 2. Echioidin blocks NF-kB p65 translocation to cool high fever spikes. 3. Antiviral envelope inhibition.
Preparation & Dosage
THE SOVEREIGN HEMPEDU BUMI BUKIT HEPATOPROTECTIVE DECOCTION: 10 to 15 g dried whole herb boiled with Dukung Anak (15 g) and Temulawak in 600 mL water for 20 min; taken warm twice daily for 14 days (lowers elevated ALT/AST). Snakebite poultice: 30 g fresh leaves pounded.
Appended Prescriptions
- 1. The Sovereign Viral Hepatitis & Jaundice Triad with Phyllanthus niruri (Dukung Anak) and Kunyit. 2. Acute Purulent Tonsillitis Draught with Isatis indigotica (Ban Lan Gen).
Yemama Apothecary · Petaling Jaya, Malaysia · For educational and clinical reference only
