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    Yemama Apothecary

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    Wind-Damp Dispelling, Gout-Purging & Antidiabetic Sovereign (疏风清热 / 解毒利湿消肿止痛降尿酸降血糖化痰止咳 — 传统南洋降酸止痛第一孔雀豆 / 风湿热痹与痛风克星 / 极品相思豆 / 豆科清热活血要药)

    海红豆 / 孔雀豆 / 相思豆 / 红心豆 / 细叶海红豆 — Adenanthera pavonina L. (syn. Corallaria parvifolia)

    Pinyin: Hǎihóngdòu / Kǒngquèdòu / Xiāngsīdòu · Malay: Sega Mas / Saga Daun Manis / Saga Hutan / Kacang Sega / Pohon Saga · Family: Fabaceae (豆科 / 含羞草亚科)

    Botanical Illustration

    Energetics

    Cool (微寒 / 苦涩凉; Bark/Leaves); Slightly Toxic when seeds are raw (有小毒 - Raw seeds contain lectins; roasting renders safe)

    Flavor

    Bitter, astringent, slightly sweet (苦、微涩、微甘、微凉)

    Meridians

    Liver (肝), Lung (肺), Heart (心), Spleen (脾)

    Traditional Edict

    Red Bead Tree / Love Pea (Sega Mas / Hai Hong Dou / Xiang Si Dou). Spiral black pods with glossy scarlet heart-shaped seeds. Dual-Action Sovereign for Gout & Arthritis: competitively inhibits Xanthine Oxidase to dissolve joint tophi and lower uric acid, while moderating glucose.

    Cautions & Contraindications

    • NEVER INGEST RAW UNCOOKED SEEDS (contains heat-labile phytohemagglutinin lectins; thorough roasting/cooking is mandatory). CONTRAINDICATED in active pregnancy for internal decoctions.

    Clinical Applications

    • Hyperuricemia and acute gouty arthritis (potent Xanthine Oxidase inhibition via Ampelopsin), rheumatoid arthritis and knee stiffness, Type 2 Diabetes mellitus, and boil drawing.

    Quality Markers

    Ampelopsin (蛇葡萄素) >= 0.60%, Pavoninin & Total Polyphenols >= 2.50% (HPLC MHM standard)

    Mechanism & Phytochemistry

    1. Ampelopsin competitively inhibits hepatic Xanthine Oxidase (IC50=4.8 ug/mL), blocking uric acid synthesis. 2. Suppresses macrophage NLRP3 inflammasome. 3. Roasting denatures raw toxic lectins.

    Preparation & Dosage

    CRITICAL PAOZHI MANDATE: ROASTED SEEDS (Chao Hai Hong Dou): Seeds must be roasted at 120C for 30 min (or boiled 45 min). THE SOVEREIGN SEGA MAS ANTI-GOUT DECOCTION: 15 to 20 g dried bark or roasted seeds boiled with Misai Kucing and Sidaguri in 600 mL water for 25 min.

    Appended Prescriptions

    • 1. The Sovereign Nanyang Anti-Gout Triad with Sida rhombifolia (Sidaguri) and Orthosiphon. 2. Osteoarthritis Joint-Dredging Draught with Tinospora sinensis (Kuan Jin Teng).

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    Yemama Apothecary · Petaling Jaya, Malaysia · For educational and clinical reference only